Managing the Inevitable Surge of Post–COVID-19 Functional Gastrointestinal Disorders

Maddrey discriminant function — Disease severity and mortality risk in patients with alcoholic hepatitis may be estimated using the Maddrey discriminant function (DF, also known as the Maddrey score), which is calculated as follows (calculator 1) [15,16]:

For bilirubin in conventional units (mg/dL):

DF = (4.6 x [prothrombin time (sec) – control prothrombin time (sec)]) + (serum bilirubin)
For bilirubin in système international units (micromol/L):

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Patients with a DF value ≥32 have high short-term mortality and may benefit from treatment with glucocorticoids, whereas those with lower scores have low short-term mortality and do not appear to benefit from glucocorticoids